NCIRS plays a leading role in surveillance methodology and reporting related to vaccine preventable diseases (VPDs), immunisation coverageadverse events following immunisation and seroepidemiology.

A range of regular national surveillance reports are produced, based on data from several national datasets. Data are obtained through collaborations with other organisations, outlined in more detail in relevant website pages in this surveillance section.

NCIRS plays a leading role in surveillance methodology (both design and analysis) through its contribution to the work of the Communicable Diseases Network Australia, and all its relevant subcommittees related to VPD surveillance, and through specific NCIRS reports and publications. Relevant longstanding subcommittees include the National Surveillance Committee, Case Definitions Working Group and Polio Elimination Committee, while others have been convened for defined periods to develop national surveillance plans for particular diseases such as varicella, rotavirus and HPV.

NCIRS has also led collaborations to develop new surveillance systems, such as the National Serosurveillance Program and the Paediatric Active Enhanced Disease Surveillance (PAEDS) network.

Surveillance and immunisation coverage data also form major components of national immunisation program evaluations which are carried out by NCIRS.